High-sensitivity cardiac troponin testing in routine practice: economic and organizational advantages

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Clinical, organizational and economic analysis of high-sensitivity cardiac troponin testing in the emergency department

The measurement of cardiac troponins (cTns) has become the mainstay for the diagnosis of acute coronary syndrome (ACS), since the assessment of either cardiac troponin T (cTnT) or cardiac troponin I (cTnI) has now outperformed whatever other available biomarker, to be used alone or in combination with cTns (1). This paradigm shift has been strongly supported by recent introduction in clinical p...

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High sensitivity cardiac troponin testing.

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High-sensitivity cardiac troponin: from theory to clinical practice.

Since 2000, cardiac troponin (cTn) has been the recommended biomarker for the evaluation of patients with a possible diagnosis of acute myocardial infarction (AMI). Most of the cTn immunoassays currently in use lack the analytical sensitivity to accurately measure the upper reference limit (URL), ie, the 99th percentile reference value, which is the guideline-mandated cutoff value for myocardia...

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Stressing the Utility of High-Sensitivity Cardiac Troponin Testing in Patients with Possible Cardiac Ischemia

Strategies to rule out myocardial infarction (MI)2 in the emergency department include stress test echocardiography, electrocardiography, and assessment of cardiac biomarkers such as troponin I and T (1). The potential for new high-sensitivity cardiac troponin testing to simplify and expedite these rule-out protocols is of great interest. Is all the hype justified? Or are we placing unreasonabl...

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ژورنال

عنوان ژورنال: Annals of Translational Medicine

سال: 2016

ISSN: 2305-5839,2305-5847

DOI: 10.21037/atm.2016.07.04